Andrea d'Agnolo, called Sarto (his father was a tailor), born on 16 July 1486 in Florence, where he studied probably with Rafaellino del Garbo (though Vasari said Piero di Cosimo), before sharing a studio with Franciabigio from c. 1506. In 1508 they were joined by the sculptor Jacopo Sansovino, and on 8 December that year Sarto was admitted to the Arte de' Medici e Speziali.
He married c. 1517 a widow, Lucrezia del Fede (d. 1570), who survives in romantic literature as a demanding, unattractive partner. Between May 1518 and October 1519 he was in Fontainebleau at the command of François I who was displeased by Sarto's premature return to Florence. He died in Florence where he was buried on 29 September 1530.