Born on 9 June 1799 in Warneton, West Flanders, son of the sculptor Barthelemev Verboeckhoven (1754-1840), from whom he received some instruction in modelling and lithography. Subsequently, influenced by the work of Potter and Cuyp and the teaching of B. P. Ommeganck at the Ghent Academy, he became an animalier in the seventeenth-century tradition, his style changing little in the course of a long career.
He first exhibited at Ghent in 1820. He travelled in France (1824 and 1841), Germany (1828) and Italy (1841) and visited London in 1824 and 1826. In 1827 he settled in Brussels where T. S. Cooper was his pupil, and where he fought in the War of Independence in 1830. He was made chevalier of the Legion of Honour and of the Order of Leopold, and became a member of the Brussels Academy in 1845. He died at Schaerbeek, Brussels, on 19 January 1881.